Provigrax - The Science Behind....

The Science Behind ProVigraX...

Erectile dysfunction
Also known as ED and impotence, the loss of the ability to produce and/or sustain an erection despite adequate stimulation and interest.

The penis is made up of 3 chambers, two corpora cavernosa – the erectile tissues and one corpus spongium. Secretion of nitric oxide (NO) leads to sexual arousal, blood vessels dilate and blood fills the penis. This typically lasts until arousal is diminished or orgasm is achieved. Penile erection is mediated by the nervous system. On stimulation causes vasodilatation and relaxation of the cavernosal (penis) smooth muscle, which ultimately leads to penile erection. Nitric oxide is released from nerve endings by activating guanylate cyclase and resulting into cGMP which is the secondary messenger that causes smooth muscles relaxation leads to venous engorgement and penile tumescence. Recent research has helped to change our thinking about the most common causes of sexual dysfunction. For a long time it was assumed that almost all erection failures were caused by psychological factors -- stress, anxiety, and fear. While these factors can play a significant role, most experts now believe the major cause of impotence is physical. Simply stated, anything that interferes with blood flow to the sexual organs interferes with sexual function. It was presumed that almost all erection failures were caused by physiological factors like stress, fear, anxiety etc. Though these factors play a significant role, recent researches also indicate impotence as physical inability of blood flow to the penis.

Physical causes of erectile dysfunction:
• Excess use of alcohol and tobacco/nicotine
• Fatigue/anxiety/stress
• Brain or spinal-cord injuries
• Low testosterone levels i.e. Hypogonadism
• Parkinson's disease
• Radiation therapy to the testicles
• Heart stroke/s
• Some types of prostate or bladder surgery
• Hyperglycemia (high blood sugar)
• Hypertension (high blood pressure)

Feelings that can lead to erectile dysfunction
• Nervousness about sex. It could be a result of bad experience or past episode of impotence.
• Stress related to work/family
• Problems in the relation with sex partner
• Depression
• Consciousness and negative feelings

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Testosterone and Sex Drive
As age increases, men usually suffer from low sex drive, poor stamina and lack of sexual interest, because most of the testosterone gets bound by sex hormone building globulin. Only 2% of testosterone are left free which are responsible for providing the body with energy and sex drive. Normal men should have 800 free testosterone and lesser number calls for erectile dysfunction.
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Epimedium
Epimedium Or Horny Goat Weed holds an important place in traditional Chinese medicine, now gaining popularity throughout the world for its role in restoring sexual life, boosting erectile function, allaying fatigue and depression.

Termed as most valuable herbal tonic, epimedium supports healthy sexual activity, helps boost libido and improve erectile function. It works by freeing up testosterones which are responsible for sex drive and endurance. It tones up kidneys and reduces symptoms of impotence, frequent urination and lower back pain.

Clinical researches prove that epimedium increase sexual activity, enhance sperm production and have a moderate androgen like influence on the testes, prostate gland and genital muscles thus influencing desire and interest for sexual activity.

Researches also show that Epimedium can inhibit an enzyme called acetylcholinesterase (AChE). By inhibiting AChE, Epimedium supports higher levels of the key cholinergic neurotransmitters associated with sexual arousal.

Trials prove that usage of epimedium elevates the levels of noradrenalin, adrenaline, serotonin and dopamine, thus encouraging release of LH which in turn stimulates testes to produce more testosterone. Also associated with stimulation of sensory nerves particularly genital region.

MACA (Lepidium meyenii)
Maca is an all-natural herbal wonder from Peru with a legendary history for its use to increase sexual ability, pleasure, endurance, mental clarity and most important as an aphrodisiac. Maca contains 50 naturally occurring phyto-chemicals including vital hormonal precursors and sterols proven to assist the human body. It is also an adaptogen and creates homeostasis in the body, regulates levels of hormones and enzymes. Also supports enhanced libido, improved potency, fertility and increased DHEA & testosterone levels. It helps overcome depression and alleviate stress.

Maca is a wonderful source of natural vital nutrients. The synergy of so many amino acids, vitamins, and minerals in their natural states may increase the assimilation, uptake, and utilization of them in the body. That’s why Maca is a powerful adaptogen immunostimulant that help balance our body's systems, stabilize blood pressure, boost immunity and harmonize the body's overall vitality.

Primary uses of Maca
1. Aid in fertility and as aphrodisiac
2. Energize and revitalize physical and mental strength

Doctor's Comments on Maca
Gary F. Gordon, M.D., former President of the American College for Advance Medicine, now founder and president of the International College of Advanced Longetivity Medicine, located in Chicago, Illinois, know first hand the value of Maca. "We all hear rumors about various products like Maca," he says. "But using this Peruvian root myself, I personally experienced a significant improvement in erectile tissue response.”

Dr. Gordon explains that Maca works by normalizing our steroid hormones like testosterone, progesterone, and estrogen. Therefore it has the facility to forestall the hormonal changes of aging. It acts on men to restore them to a healthy functional status in which they experience a more active libido. While at the same time relaxes the penile muscles thereby allowing blood flow into the penile muscle tissue causing a hard erection